Instillation of hyaluronic acid via a catheter into the bladder contributes to the recovery of the urothelial mucosa. It is indicated in cases of painful bladder, interstitial cystitis, chemical cystitis, recurrent cystitis, or radiation cystopathy.
Bladder instillations are the administration of drugs through the bladder so that they act directly on the superficial layers of the bladder.
One of the drugs commonly administered intravesically is hyaluronic acid, which helps restore the urothelial layers and allows for the recovery of the glycosaminoglycan layer. It is particularly indicated in cases of painful bladder syndrome, interstitial cystitis, chemical cystitis, recurrent urinary tract infections, or radiation cystopathy.
It is an outpatient treatment, painless. It usually requires twelve sessions; the first four are weekly, and then they are administered every two weeks.
Administration depends on whether or not the patient has a urinary catheter. If they do, the bag connected to the catheter is removed, and the fluid from the syringe is administered. The cap is then inserted to retain the medication in the bladder for as long as possible; approximately thirty minutes is recommended.
When the patient does not have a catheter, a urethral catheter is inserted through which, once the bladder is completely empty, the medication is administered. The medication is then eliminated in the urine.
