Dr. José Francisco Flores Martín

Dr. José Francisco Flores Martín is an expert in minimally invasive urological surgery, with extensive experience in endoscopic, percutaneous, and laser techniques for the treatment of urinary stones and tumors of the urinary tract. He also specializes in the advanced diagnosis of prostate cancer.

Dr. José Francisco Flores Martín is a urologist with a degree in Medicine from the Miguel Hernández University of Elche. He completed his residency in Urology between 2010 and 2015 at the Virgen de las Nieves University Hospital in Granada. He has a strong academic background, including a PhD in Biomedicine from the University of Granada, awarded with the highest distinction, and several master's degrees in Functional Urology, Renal Cancer, and Prostate Cancer from the University of Salamanca. He has been a Fellow of the European Board of Urology (FEBU) since 2015 and has specialized training in laparoscopic and advanced urological surgery.

Current specialization

The doctor is an expert in minimally invasive, endoscopic, percutaneous, and laser surgery for the treatment of urinary stones and tumors of the upper and lower urinary tract. He is also an expert in advanced techniques for diagnosing prostate cancer.

Academic activities and membership in organizations

Dr. Flores has been a member of the Andalusian Association of Urology (AAU) since 2012, as well as the Spanish Association of Urology (AEU). He actively participates in research as a member of the IBS A-08 Research Group “Immune Response and Cancer. Mechanisms of Escape from the Immune Response” at the Granada Institute for Biomedical Research. In addition, since 2020, he has collaborated as a scientific reviewer for the journal Spanish Archives of Urology.

Scientific activity

Participation in Clinical Trials: Public and Private Calls for Proposals

Collaborating Researcher: Title: Study of candidate genes in prostate cancer. A new treatment strategy.
Participation as a Collaborating Investigator (CI) in the study: “ENCORE-01. Assessment of progression-free survival in patients diagnosed with high-risk non-muscle-invasive bladder cancer (NMIBC) treated with adjuvant IMUNO BCG Moreau RJ”. Sponsor: FIU and Biofabri SL. EUDRACT No.: 2017-002928-24
Participation as a Collaborating Investigator (CI) in the study: HLA class I in metastatic progression and resistance to new generation immunotherapy: Implications in cancer immune escape. Carlos III Health Institute. 2014-2017.
Participation as a Collaborating Investigator (CI) in the Observational Study on the management in clinical practice of castration-resistant prostate cancer with unknown metastatic status: AFRODITA Study

Awards:

First prize for best oral presentation: The combination of HLA-I positivity and PD-L1 negativity in tumor cells provides an immune rejection mechanism in bladder cancer. José Francisco Flores-Martín et al. Andalusian Congress of Urology 2019.
3 rd price for best original paper in 2016 during the XXXIX Edition of Pérez Castro Price of the Journal Archivos Españoles de Urología for “Cold ischemia time and graft survival A paired analysis. Arch. Esp. Urol. 2016; 69 (3): 121-127.
Best Poster during the XXVIIIth Congress of the Andalusian Association of Urology. Jerez de la Frontera. 15-16th October 2015. Title: How many patients meet CHAARTED criteria in our routine clinical practice during a year?”

Scientific production:
Press here to learn about their scientific output

Finally, Dr. Flores has developed a distinguished scientific career, serving as lead author or co-author on more than ten book chapters. He has presented over ten papers at international conferences, more than thirty at national conferences, and just as many at regional conferences, consistently ranking among the top three authors.

Diseases it treats

Benign Prostate Hyperplasia

Growth of a benign tumor in the prostate gland as a result of aging. It produces urinary symptoms such as difficulty starting urination, weak stream, frequency, urgency, needing to get up to urinate at night, or incontinence.

Kidney Stones

The crystallization of waste products in urine can produce kidney stones. These stones can vary in composition and their elimination may occur naturally or require surgical treatment.

Bladder Cancer

Very common in patients who smoke or who smoked in their youth, it usually presents with blood in the urine and irritative urinary symptoms. 80% of cases are curable.

Phimosis

Narrowing of the foreskin that prevents the glans from being exposed. This can compromise hygiene and cause discomfort during sexual intercourse. It is common in children but sometimes bothers older men as well.

Testicular Cancer

It is a cancer that primarily affects young men. It can be of different types depending on the type of cell it affects, and its main symptom is the appearance of a painless lump in the testicle.

penile cancer

It is a rare cancer, curable when detected early; its detection is difficult in uncircumcised men; you should consult a doctor if you notice any lump or ulcer on the penis, discharge, or bleeding.

Techniques in which he specializes

Flowmetry

This test measures the amount of urine the patient's bladder is able to urinate per second, the duration of urination, and any possible interruptions during urination.

Prostate mapping

Fusion biopsy projects the prostate MRI images onto those obtained in real time in the operating room with ultrasound and allows the biopsy to be directed with great precision to the areas of suspicion of cancer.

urological ultrasound

It allows visualization of the body's interior without the use of radiation, thanks to the use of ultrasound. It can be used to view the kidneys, adrenal glands, parts of the ureters, bladder, prostate, testicles, urethra, and penis.

4K Cystoscopy

It is a diagnostic procedure that allows visualization of the urethra and bladder using a high-resolution cystoscope (a thin tube connected to a camera). It allows the urologist to identify suspicious lesions.

Image fusion prostate biopsy

It is a technique that combines 3-tesla magnetic resonance imaging with ultrasound. This fusion increases the biopsy yield, improving and refining tumor diagnosis.

Varicocelectomy

This procedure involves ligating testicular varicosities, or varicoceles, through a small incision in the groin. It is usually performed in cases where the patient experiences testicular pain or decreased fertility.

Hydrocelectomy

Surgical intervention that resolves the excessive accumulation of fluid around the testicle (hydrocele).

Bladder instillations of hyaluronic acid

Instillation of hyaluronic acid via a catheter into the bladder contributes to the recovery of the urothelial mucosa. It is indicated in cases of painful bladder, interstitial cystitis, chemical cystitis, recurrent cystitis, or radiation cystopathy.

Condyloma removal surgery

Genital warts can be removed with an electric scalpel using local anesthesia, by using liquid nitrogen, which destroys them by freezing (cryotherapy), or by using laser light.

Ureteral catheter or stent

It is a tubular catheter, which is inserted into the ureter, connecting the bladder and kidney, to allow urine to flow down to the bladder.

Ureteral stone surgery

Today, painful kidney stones can be treated with a simple procedure. A very thin instrument is inserted through the urethra, allowing the stones to be pulverized with a laser.

Retrograde intrarenal surgery (RIRS)

A minimally invasive endoscopic procedure that allows a very narrow and flexible instrument, which carries a camera, to be inserted through the urethra and up to the kidney, allowing kidney stones to be pulverized and extracted.

Percutaneous nephrolithotomy

Minimally invasive treatment of large kidney stones, through a puncture a camera and a laser are introduced into the kidney to pulverize the urinary stones.

Laparoscopic and robotic pyeloplasty

Laparoscopic or robotic pyeloplasty is a minimally invasive surgical procedure performed to treat strictures at the junction between the renal pelvis and the ureter. The procedure reconstructs this junction to allow urine to flow…

Transurethral resection of the bladder

This procedure allows examination of the inside of the bladder, taking biopsies or removing tumors from this organ under anesthesia.

ExactVU™ micro-ultrasound guided prostate biopsy

High-detail prostate ultrasound with micro-ultrasound allows obtaining images with a resolution 300 times greater than conventional ultrasound, and visualizing areas suspicious for cancer in the prostate, to guide biopsies with great precision.